Publication by Luca Ferrarese & Michael Koch et al.: Inflammatory mediators suppress FGFR2 expression in human keratinocytes to promote inflammation.

Ferrarese/Koch show that loss of FGFR2 in human keratinocytes promotes the expression of pro-inflammatory genes and that expression of FGFR2 itself is downregulated in keratinocytes exposed to pro-inflammatory stimuli, similarly to lesional skin of atopic dermatitis patients.