Publication by Müller et al.: Argonaute proteins: from structure to function in development and pathological cell fate determination

The highly conserved Argonaute (AGO) protein family members play a central role in the regulation of gene expression networks, orchestrating the establishment and the maintenance of cell identity throughout the entire life cycle. Here, we review the roles of AGO during early development by focusing on the interplay between specific domains of the protein and their function. Moreover, we report recent works highlighting the importance of AGO post-translational modifications in cancer.