Publications

Lyons, G. E., Muhlebach, S., Moser, A., Masood, R., Paterson, B., Buckingham, M. E., and Perriard, J. C. (1991). Developmental regulation of creatine kinase expression by myogenic factors in embryonic mouse and chick skeletal muscle. Development, 113, 1017-1029.

Billeter, R., Messerli, M., Wey, E., Puntschart, A., Jostarnd, K., Eppenberger, H. M., and Perriard, J. C. (1992). Fast Myosin Light Chain Expression in Chicken Skeletal Muscles Studied by "in situ" Hybridization. J. Histochem. Cytochem., 40, 1547-1557.

Perriard, J. C., von Arx, P., Bantle, S., Eppenberger, H. M., Eppenberger-Eberhardt, M., Messerli, M., and Soldati, T. (1992). Molecular analysis of protein sorting during biognesis of muscle cytoarchitecture. In: A. El Haj (Ed.), Molecular Biology of Muscle (pp. 219-235). Cambridge, UK.: Society for Developmental Biology.

Messerli, M., van der Voort, H. T. M., Rungger-Brandle, E., and Perriard, J.-C. (1993). Three-Dimensional Visualization of Multi-Channel Volume Data: The amSFP Algorithm. Cytometry, 14, 725-735. Messerli, J.M., Eppenberger, M.E., Rutishauser, B., Schwarb,P., Eppenberger, H.M., and Perriard, J.-C. (1993). Remodeling of Cardiomyocyte Cytoarchiteture Visualized by 3D Confocal Microscopy. Histochemistry, 100, 193-202.

Perriard, JC: (1993). Myomesin and M-protein. In Kreis.T., Vale R, eds. Guidebook to the Cytoskeletal and Motor Proteins. Oxford, Oxford University Press, pp. 58-59. Perriard, JC: (1993). Sarcomeric MM-creatine kinase. In Kreis.T., Vale R, eds. Guidebook to the Cytoskeletal and Motor Proteins. Oxford, Oxford University Press, pp. 71-72.

Muhlebach, S.M., Gross, M.,Wirz, T., Wallimann, T., Perriard, J.-C., and Wyss, M. (1994). Sequence homology and structure predictions of the creatine kinase isoenzymes. Mol. Cell. Biochem.133/134, 245-262.

Messerli, M., and J.-C., Perriard. (1995). Three dimensional analysis and visualization of myofibrillogenesis in adult cardiomyocytes by confocal microscopy. Microscopy Res. & Tech., 30., 521-530.

Kraft, T., Messerli, M., Rutishauser, B., Perriard, J.-C., Wallimann, T., and Brenner, B. (1995). Equilibration and exchange of fluorescently labelled molecules in skinned skeletal muscle fibers observed by confocal microscopy. Biophysical J., 69, 1246-1258.

von Arx, P., Bantle, S., Soldati, T., and Perriard, J.-C.(1995). Dominant Negative Effect of Cytoplasmic Actin Isoproteins on Cardiomyocyte Cytoarchitecture and Function. J. Cell Biol.131, 1759-1773.

Muhlebach, S.M., Wirz, T., Brandle, U., and Perriard, J.-C. (1996). Evolution of CK genes and their expression in chicken tissues and embryonic development. J.Biol. Chem. 271, 11920-11929.

Komiyama, M., Soldati, T., von Arx, P., and Perriard, J.-C. (1996). The intracompartmental sorting of myosin alkali light chain isoporteins reflects the sequence of developmental expression as determined by double epitope-tagging competition. J. Cell Sci. 109, 2089-2099

Bantle, S.,Keller, S., Haussmann, I., Auerbach, D., Perriard, E., Muhlebach, S., and Perriard, J.-C. (1996). Tissue specific isoforms of chicken myomesin are generated by alternative splicing. J. Biol. Chem. 271, 19042-19052

Arber, S., Hunter, J. J., Ross, J. J., Hongo, M., Sansig, G., Borg, J., Perriard, J.-C., Chien, K. R. and Caroni, P. (1997). MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, and heart failure. Cell, 88, 393-403.

Auerbach, D., Rothen-Rutishauser, B., Bantle, S., Leu, M., Ehler, E., Helfman, D. and Perriard, J.-C. (1997). Molecular mechanisms of myofibril assembly in heart. Cell Struct. Function, 22, 139-146.

Becker, K. D., Gottshall, K. R., Hickey, R., Perriard, J.-C. and Chien, K. R. (1997). Point mutations in human b-cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: An ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutatation display normal assembly. J. Cell Biol., 137, 131-140.

Bohner, V., Langguth, P., Ottiger, C., Wunderli-Allenspach, H., Rognan, D., Rothen-Rutishauser, B., Perriard, J.-C., Lang, S., Biber, J. and Merkle, H. P. (1997). Structure-permeation relations of Met-enkephalin peptide analogues on absorption and secretion mechanisms in Caco-2 monolayers. J. Pharm. Sci., 86, 846-853.

Mounier, N., Perriard, J.-C., Gabbiani, G., and Chaponnier, C. (1997). Transfected muscle and non-muscle actins are differentially sorted by cultured smooth muscle and non-muscle cells. J. Cell Science, 110, 839-846.

Rothen-Rutishauser, B., Ehler, E., Perriard, E., Messerli, M. and Perriard, J.-C. (1998). Different behaviour of the non-sarcomeric cytoskeleton in neonatal and adult rat cardiomyocytes. J. Mol. Cell. Cardiol. 30, 19-31.

Götz, J., Probst, A., Ehler, E., Hemmings, B. and Kues, W. (1998). Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Ca. Proc. Natl. Acad. Sci. USA 95, 12370-12375.

Helfman, D. M., Berthier, C., Grossman, J., Leu, M., Ehler, E., Perriard E. and Perriard, J.-C. (1999). Nonmuscle tropomyosin-4 requires coexpression with other low molecular weight isoforms for binding to thin filaments in cardiomyocytes. J. Cell Sci. 112, 371-380.

Ehler, E., Rothen, B.M., Hämmerle, S.P., Komiyama, M. and Perriard, J.-C. (1999). Myofibrillogenesis in the developing chicken heart: Assembly of Z-disk, M-line and the thick filaments. J. Cell Sci. 112, 1529-1539.

Ehler, E. and Perriard J.-C. (2000). Cardiomyocyte cytoskeleton and myofibrillogenesis in healthy and diseased heart. Heart Failure Reviews 5, 259-269

Ferrari, A., Ehler, E., Nitsch, R.M. and Götz, J. (2000). Immature human NT2 cells grafted into mouse brain differentiate into neuronal and glial cell types. FEBS Lett., 486, 121-125

Ehler, E., Horowits, R., Zuppinger, C., Price, R.L., Perriard, E., Leu, M., Caroni, P., Sussman, M., Eppenberger, H.M. and Perriard, J.-C. (2001). Alterations at the intercalated disk associated with the absence of muscle LIM protein. J. Cell Biol. 153, 763-772

Potthast, R., Ehler, E., Scheving, L.A., Sindic, A., Schlatter, E. and Kuhn, M. (2001). High salt intake increases uroguanylin expression in mouse kidney. Endocrinology, 14, 3087-3097

Young, P., Ehler, E. and Gautel, M. (2001). Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly. J. Cell Biol., 154, 123-136

Leu, M., Ehler , E. and Perriard, J.-C. (2001): Characterization of postnatal growth of the murine heart . Anat. Embryol 204, 217-224

Magyar, J.P., Nemir, M. , Ehler, E. , Suter, N. , Perriard, J-C. andEppenberger H.M. (2001): Mass production of embryoid bodies in microbeads. Ann. NY Acad. Sci. 944, 135-143

Ehler, E. and Perriard, J.-C. (2001): Emergence of the first myofibrils and targeting mechanisms directing sarcomere assembly in developing cardiomyocytes. In "Myofibrillogenesis (ed. D. K. Dube), Birkhäuser, Boston, Basel, Berlin 2001, 41-58

Dätwyler, D.A., Magyar, J.P., Busceti, V., Hirschy, A., Perriard, J.-C., Bailey, J.E. and Eppenberger, H.M. (2001): Recombinant Sindbis virus allows expression and precise targeting of proteins of the contractile apparatus in cultured cardiomyocytes. Basic Res Cardiol 96, 630-635

Ehrengruber, M.U., E. Ehler, M.A. Billeter, and H.Y. Naim. 2002. Measles virus spreads in rat hippocampal neurons by cell-to-cell contact and in a polarized fashion. J Virol. 76:5720-8.

Fielitz, J., A. Dendorfer, R. Pregla, E. Ehler, H.R. Zurbrugg, J. Bartunek, R. Hetzer, and V. Regitz-Zagrosek. 2002. Neutral endopeptidase is activated in cardiomyocytes in human aortic valve stenosis and heart failure. Circulation. 105:286-289.

Kuhn, M., R. Holtwick, H.A. Baba, J.C. Perriard, W. Schmitz, and E. Ehler. 2002. Progressive cardiac hypertrophy and dysfunction in atrial natriuretic peptide receptor (GC-A) deficient mice. Heart. 87:368-74.