The paper increases resolution of the multiplexed imaging method imaging mass cytometry (IMC). This is achieved by modified laser acquisition settings and computational deconvolution of oversampled data. High-resolution IMC enables us to analyze subcellular features across multiple biological systems.
The study identifies a poor-prognosis basoluminal tumor cell phenotype in triple-negative breast cancer and proposes a novel patient stratification system based on tumor cytokeratin expression and tumor-immune interactions.
We are welcoming Prof. Kim Bak Jensen, Professor and Executive Node Director at the Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen on Thursday, January 29th, 2026, at 9.45 a.m., HPM H33 for a talk entitled: "Guiding intestinal epithelial stem cell fate in health and disease".