Prof. Dr. Bernd Bodenmiller

Quantitative Biomedicine

Single-cell systems biology of cancer requires methods to measure multiple markers within tumors, quantitatively and at single-cell resolution. To this end, the Bodenmiller group has pioneered a single-cell mass spectrometric imaging approach called "imaging mass cytometry". This technology allows the simultaneous and high-throughput imaging of approximately 50 markers, including proteins, their modifications, and transcripts on single cells in tissues in situ. The Bodenmiller group employs mass cytometry-based methods to study the cellular composition and regulation of tissue ecosystems, for insights into health and disease.